What to do if your lymph nodes in your neck are swollen

Swollen glands; Glands - swollen; Lymph nodes - swollen; Lymphadenopathy

Table of Contents Show

Considerations
When to Contact a Medical Professional
What to Expect at Your Office Visit
References
Version Info
When should I worry about swollen lymph nodes in neck?
What causes swollen lymph nodes in the neck?
Are swollen lymph nodes in neck serious?
How long does it usually take for swollen lymph nodes to go away?

Lymph nodes are present throughout your body. They are an important part of your immune system. Lymph nodes help your body recognize and fight germs, infections, and other foreign substances.

The term "swollen glands" refers to enlargement of one or more lymph nodes. The medical name for swollen lymph nodes is lymphadenopathy.

In a child, a node is considered enlarged if it is more than 1 centimeter (0.4 inch) wide.

The lymphatic system has two main functions. Its network of vessels, valves, ducts, nodes, and organs helps balance the body's fluid by draining excess fluid, known as lymph, from the body's tissue and returning it to the blood after filtering it. Some types of blood cells are also made in the lymph nodes. The lymphatic system also plays an important role in the body's immune system. Infection, even a trivial infection is, the most common cause of swollen lymph nodes. Let's look at a cut section of a lymph node to see what happens. Afferent means towards. Afferent lymph vessels bring unfiltered fluids from the body into the lymph node where they are filtered. Efferent vessels, meaning away from, carry the clean fluid away and back to the bloodstream where it helps form plasma. When the body is invaded by foreign organisms, the swelling sometimes felt in the neck, armpits, groin, or tonsils comes from the microorganisms trapped inside the lymph nodes. Eventually, these organisms are destroyed and eliminated by cells that line the node walls. Then the swelling and pain subside.

The lymphatic system filters fluid from around cells. It is an important part of the immune system. When people refer to swollen glands in the neck, they are usually referring to swollen lymph nodes. Common areas where lymph nodes can be easily felt, especially if they are enlarged, are the groin, armpits (axilla), above the clavicle (supraclavicular), in the neck (cervical), and the back of the head just above hairline (occipital).

Swollen lymph nodes, sore throat, fatigue and headache are some of the symptoms of mononucleosis, which is caused by the Epstein-Barr virus. It is generally self-limiting and most patients can recover in 4 to 6 weeks without medicines.

The lymphatic system is a complex system of fluid drainage and transport, and immune response and disease resistance. Fluid that is forced out of the bloodstream during normal circulation is filtered through lymph nodes to remove bacteria, abnormal cells and other matter. This fluid is then transported back into the bloodstream via the lymph vessels. Lymph only moves in one direction, toward the heart.

Lymph nodes produce immune cells to help fight infection. They also filter the lymph fluid and remove foreign material, such as bacteria and cancer cells. They can become swollen from inflammatory conditions, an abscess, cancer, and most commonly from infection. Common areas where lymph nodes can be felt include the groin, armpit, behind the ears, back of the head, sides of the neck and under the jaw and chin.

Lymph nodes play an important part in the body's defense against infection. Swelling might occur even if the infection is trivial or not apparent. Swelling of lymph nodes generally results from localized or systemic infection, abscess formation, or malignancy.

Considerations

Common areas where the lymph nodes can be felt (with the fingers) include:

Groin
Armpit
Neck (there is a chain of lymph nodes on either side of the front of the neck, both sides of the neck, and down each side of the back of the neck)
Under the jaw and chin
Behind the ears
On the back of the head

Causes

Infections are the most common cause of swollen lymph nodes. Infections that can cause them include:

Abscessed or impacted tooth
Ear infection
Colds, flu, and other infections
Swelling (inflammation) of gums (gingivitis)
Mononucleosis
Mouth sores
Sexually transmitted illness (STI)
Tonsillitis
Tuberculosis
Skin infections

Immune or autoimmune disorders that can cause swollen lymph nodes are:

HIV
Rheumatoid arthritis (RA)

Cancers that can cause swollen lymph nodes include:

Leukemia
Hodgkin disease
Non-Hodgkin lymphoma

Many other cancers may also cause this problem.

Certain medicines can cause swollen lymph nodes, including:

Seizure medicines, such as phenytoin
Typhoid immunization

Which lymph nodes are swollen depends on the cause and the body parts involved. Swollen lymph nodes that appear suddenly and are painful are usually due to injury or infection. Slow, painless swelling may be due to cancer or a tumor.

Home Care

Painful lymph nodes are generally a sign that your body is fighting an infection. The soreness usually goes away in a couple of days without treatment. The lymph node may not return to its normal size for several weeks.

When to Contact a Medical Professional

Contact your health care provider if:

Your lymph nodes do not get smaller after several weeks or they continue to get larger.
They are red and tender.
They feel hard, irregular, or fixed in place.
You have fever, night sweats, or unexplained weight loss.
Any node in a child is larger than 1 centimeter (a little less than half inch) in diameter.

What to Expect at Your Office Visit

Your provider will perform a physical examination and ask about your medical history and symptoms. Examples of questions that may be asked include:

When the swelling began
If the swelling came on suddenly
Whether any nodes are painful when pressed

The following tests may be done:

Blood tests, including liver function tests, kidney function tests, and CBC with differential
Lymph node biopsy
Chest x-ray
Liver-spleen scan

Treatment depends on the cause of the swollen nodes.

References

Tower RL, Camitta BM. Lymphadenopathy. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 517.

Winter JN. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 159.

Version Info

Last reviewed on: 1/29/2022

Reviewed by: Linda J. Vorvick, MD, Clinical Associate Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

When should I worry about swollen lymph nodes in neck?

See your GP if you have swollen glands and: they feel hard or don't move when you press them. you also have a sore throat and find it difficult to swallow or breathe. you also have unexplained weight loss, night sweats or a persistent high temperature (fever) you don't have an obvious infection and don't feel unwell.

What causes swollen lymph nodes in the neck?

Swollen lymph nodes usually occur as a result of infection from bacteria or viruses. Rarely, swollen lymph nodes are caused by cancer. Your lymph nodes, also called lymph glands, play a vital role in your body's ability to fight off infections.

Are swollen lymph nodes in neck serious?

Swollen lymph nodes can be a literal pain in the neck. But more often than not, minor infection or illness is the cause. They should go away as soon as your condition clears up. If you have swollen lymph nodes that don't go away or seem to grow over time, see your healthcare provider.