In our latest question and answer, the pharmacist discusses the difference between Tylenol Arthritis and Tylenol Extra Strength. Question What is the difference between Tylenol 500mg and 650 mg? Which is extra strength? I know there is a 'Tylenol Arthritis', but I'm not sure what it is. Asked by Doe On Jan 02, 2022 Published Jan 02, 2022 Key points
Hello and thank you for reaching out to us! There are two main differences between Tylenol Extra Strength and Tylenol Arthritis.
I discuss these differences below. Strength DifferenceThe first main difference between Tylenol Extra Strength and Tylenol Arthritis is their respective strengths:
For reference, 'regular strength' Tylenol contains 325mg acetaminophen per tablet. Below are the 'drug facts' for each product, showing the difference in strength. Now, even though Tylenol Arthritis contains more acetaminophen per dose, it is released from the tablet (or caplet) over a longer period of time than Tylenol Extra Strength, and I discuss this in the next section. Duration Of Action & DosingTylenol Arthritis is an extended-release formulation and each tablet releases acetaminophen over an 8-hour window. Tylenol Extra Strength, on the other hand, is immediate-release. Due to the differences in their drug-release mechanism, the products are recommended to be dosed as follows:
Tylenol Arthritis is sometimes referred to as 'Tylenol 8-Hour', as that is the approximate duration of action. Tylenol Extra Strength, being an immediate release product, generally lasts around 4 to 6 hours per dose. Maximum Tablets Per DayThe recommended maximum daily dose of acetaminophen is 4,000 mg per day for most adults. This equates to:
Final WordsThanks again for your question! I hope this answer helped! The takeaway is that these are both similar products, with just some slight differences in strength and duration of action. In regard to arthritis, it is more of a chronic condition, and has to be treated as such. Taking a pain reliever that releases slowly over time, and therefore lasts longer, (like Tylenol Arthritis) is generally a better option than taking something intended to be used from minor aches and pains on an 'as-needed basis' (like Tylenol Extra-Strength). The American College of Rheumatology actually recommends acetaminophen as a first-line treatment for osteoarthritis of the knee and hip, so Tylenol Arthritis, with its long duration of action, is a good choice for most individuals. Please be sure to reach out to us if anything else comes up, or if you need a recommendation on the best over-the-counter pain reliever for you. References
About the PharmacistDr. Brian Staiger, PharmDDr. Brian has been practicing pharmacy for over 11 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Feel free to send him an email at ! You can also connect with Dr. Brian Staiger on LinkedIn. What does Tylenol rapid release do?These extra strength rapid release gel caps with 500 mg acetaminophen feature laser-drilled holes to release medicine quickly, and help treat minor aches and pains related to headache, backache, minor arthritis pain, toothaches, menstrual cramps, fever and more.
How long does it take for extra strength rapid release Tylenol to work?by Drugs.com
The approximate length of time it may take before you notice a reduction in your pain if Tylenol is taken on an empty stomach are: Orally disintegrating tablets, oral Tylenol liquid: 20 minutes. Oral tablets, extended-release tablets: 30 to 45 minutes. Intravenous acetaminophen: 5 to 10 minutes.
Does Tylenol Rapid Release make you sleepy?Tylenol PM Extra Strength Liquid and Tylenol PM Extra Strength Pain Reliever caplets: These products contain acetaminophen and an antihistamine called diphenhydramine HCI that can make you feel sleepy.
What is the strongest type of Tylenol?Containing 500 mg of acetaminophen, TYLENOL® Extra Strength Caplets help temporarily reduce fever in adults and children 12 years and older, and provide powerful relief of tension headaches, minor back and muscle pain, minor arthritis pain and more.
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