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Sponsor: Information provided by (Responsible Party): Kareem Medhat Mohamed Abdallah, Ain Shams University Brief Summary: Research hypothesis : In pregnant women undergoing induction of labor, intramuscular injection of dexamethasone may accelerate induction delivery interval. Research question : In pregnant women undergoing induction of labor, does intramuscular injection of dexamethasone accelerate induction delivery interval ? This study aims to assess the effect of intramuscular administration of dexamethasone on the induction delivery interval in full term patients undergoing induction of labor.
Detailed Description: The use of corticosteroids is one of the methods put forward for the strengthening and speeding up the process of labor. After identification of glucocorticoid receptors in human amnion, the role of corticosteroids in starting the process of labor has been studied in numerous studies. Some of them discussed the relation between dexamethasone injection and labor induction but still there is insufficient data. So by the end of this study it may be possible to assess the effect of intramuscular dexamethasone injection on shortening the induction delivery interval.
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Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03603418 Layout table for location information
Ain Shams University Layout table for additonal information
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Is dexamethasone harmful during pregnancy?During pregnancy, prolonged use of corticosteroids that readily cross the placental barrier like dexamethasone can negatively impact both the mother and the foetus.
When should a pregnant woman take dexamethasone injection?Conclusion: Dexamethasone accelerates maturation of fetal lungs, decrease number of neonates with respiratory distress syndrome and improves survival in preterm delivered neonates. Optimal gestational age for use of dexamethasone therapy is 31 to 34 weeks of gestation.
What are the most common side effects of dexamethasone?The most common side effects are sleep problems, mood changes, indigestion and weight gain. Tell your doctor if you come into contact with anyone who has measles, chickenpox or shingles while you're taking dexamethasone.
What are the side effects of dexamethasone injections?Dexamethasone injection may cause side effects.. headache.. slowed healing of cuts and bruises.. thin, fragile, or dry skin.. red or purple blotches or lines under the skin.. skin depressions at the injection site.. |