Probiotics with lactobacillus reuteri and lactobacillus rhamnosus

BioGaia’s probiotic products with Limosilactobacillus reuteri (formerly known as Lactobacillus reuteri) are among the most scientifically well-documented probiotics in the world. To date the efficacy and safety of BioGaia’s different strains of L. reuteri have been documented in 224 clinical studies in around 18,000 people of all ages (May 2020).

BioGaia’s strains of L reuteri has been tested in 110 studies in children, from newborns up to 18 years old, and in 114 studies in adults.

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Our probiotic strains with L. reuteri

 L. reuteri Protectis (L. reuteri DSM 17938)

  • For gut comfort
  • 152 completed clinical trials in 14 800 individuals

 L. reuteri Prodentis (L. reuteri DSM 17938 and L. reuteri ATCC PTA 5289)

  • For gums and teeth
  • 42 completed clinical trials in 2 065 individuals

L. reuteri Gastrus (L. reuteri DSM 17938 and L. reuteri ATCC PTA 6475)

  • For GI tract
  • 8 clinical trials

L. reuteri Osfortis (L. reuteri ATCC PTA 6475)

  • For bone health
  • 1 clinical trial

L. reuteri Colus (L. reuteri ATCC PTA 4659)

  • This product is still under development for colon health.
  • 1 clinical trial

Why choose L. reuteri?

  • L. reuteri is of human origin and one of few bacterial species that has co-evolved with humans since the beginning.
  • Our L. reuteri products are of the highest quality and are manufactured under controlled conditions.
  • Efficacy and safety are tested and documented in the target populations, from newborns to the elderly.
  • Our probiotics contain viable freeze-dried L. reuteri.
  • The number of live bacteria is guaranteed until expiry.
  • The probiotic bacteria are always defined on strain level.

L. reuteri survive through the whole GI tract

Many probiotics die when they encounter the acidic environment of the stomach, but L. reuteri survive throughout the entire GI tract and beyond. Samples taken from throughout the body show that L. reuteri is present in:

  • Breast milk
  • The vagina
  • The mouth
  • The stomach
  • The small intestine
  • The large intestine
  • Faeces

Where do our probiotic strains come from?

The first strain of L. reuteri for human use, L. reuteri DSM 17938, was isolated in 1990 from the breast milk of a Peruvian mother living in the Andes. Other human strains from BioGaia are L. reuteri ATCC PTA 5289, which is used in oral health products and was isolated from the oral cavity of a Japanese woman with remarkably good dental health. L. reuteri ATCC PTA 6475 is an anti-inflammatory strain isolated from the breast milk of a Finnish woman.

Today L. reuteri bacteria are produced in modern production facilities under controlled conditions to ensure that the product you buy contains exactly the same bacterial strain every time. The bacteria are cultured with the correct food and temperature to grow and duplicate. Through careful testing and quality control, each dose has the right number of viable organisms with no contaminants.

The right dose for colonisation

Even an indigenous bacterium like BioGaia’s L. reuteri Protectis should be taken on a regular basis to reach high enough levels to achieve proper colonisation and have a good effect.

Biopsies have shown that L. reuteri temporarily binds to the epithelial lining, which covers our GI tract and works like a skin on the inside of our bodies. The main task of this “inner skin” is to differentiate between what should be absorbed and what should not be let into our bodies.

The cells in our epithelial lining are replaced every fourth day, however, so the majority of L. reuteri cells are washed away within a week or so. Since L. reuteri colonisation is transient, daily intake is recommended to ensure adequate and stable levels of L. reuteri in the GI tract.

Read more about Gatekeepers in the gut

Clinical studies show that 100 million units per day is a safe and efficient dose of L. reuteri Protectis for children and adults. Each probiotic has a different recommended dose depending on which strain or strains the product contains.

Safe for all ages

Safety has been proven in babies, infants, children, healthy adults and immunocompromised adults. Even when taken at 10 billion units per day – meaning 1 000 times the recommended daily dose – no serious adverse effects have been observed.

L. reuteri throughout life

L. reuteri is a species of bacteria that is grounded in evolution. It lives in the GI tract of animals, with each species carrying its own specialised strains that are passed down through generations. Humans and their ancestors have co-evolved with their own strains of L. reuteri over millions of years.

As a result of this evolutionary process, L. reuteri contributes to human health throughout life. Humans are born almost sterile and first encounter L. reuteri during the birthing process and through breastfeeding. As a key member of the gut microbiota, L. reuteri plays an important role in helping babies to digest breast milk and solids foods. Throughout life, the bacteria tighten the lining of the gut to prevent leakage and improve immune response. They also release molecules that promote a healthy and diverse microbiota and prevent the growth of pathogens. Supporting the gut microbiota is especially important later in life, because elderly individuals tend to lose diversity in their guts.

Some people today still have L. reuteri as part of their microbiota, but many people lack these strains as a result of our modern lifestyles. A low-fibre diet, increased sanitation, antibiotic use and rising rates of birth by Cesarean section, which do not expose babies to the bacterium, have all played a role in depleting L. reuteri from our gastrointestinal (GI) tract.

People can reintroduce L. reuteri through the use of probiotics, but they must be replenished frequently, since the bacteria are continually washed out of the GI tract.

What are probiotics?

The history of BioGaia

Can Lactobacillus plantarum boost your health?

The immunomodulating properties of Lactobacillus plantarum include an increase in the level of anti-inflammatory cytokines, which reduce the risk of cancer and improve the efficacy of regimens.

What are the benefits of using Lactobacillus supplements?

What Is Lactobacillus Gasseri Used For?

  • Weight Loss. A number of clinical trials and animal-based studies have suggested that Lactobacillus gasseri may help reduce abdominal fat and support weight loss. ...
  • Vaginal Health. Lactobacillus strains are known to promote vaginal health by suppressing harmful bacteria and fungi. ...
  • Bowel Diseases. ...
  • H. ...

Does Lactobacillus plantarum cause weight loss?

While L. plantarum does not directly help with weight loss like other bacteria from the Lactobacillus family, it significantly improves gut health and promotes a stronger immune system. Exercise efforts and diet plans to lose weight work better with a healthy and balanced gut microbiome.

What is the species of Lactobacillus?

Lactobacillus is a genus of Gram-positive, aerotolerant anaerobes or microaerophilic, rod-shaped, non-spore-forming bacteria. Until March 2020, the genus Lactobacillus comprised over 260 phylogenetically, ecologically, and metabolically diverse species; a taxonomic revision of the genus in 2020 assigned lactobacilli to 25 genera (see § Taxonomy below).

Is Lactobacillus rhamnosus the same as Lactobacillus reuteri?

The key difference between Lactobacillus rhamnosus and Lactobacillus reuteri is that Lactobacillus rhamnosus is a bacterial species that may sometimes be pathogenic in people who have weakened immunity and infants, while Lactobacillus reuteri is a bacterial species that is generally non-pathogenic.

What probiotic has L. reuteri in it?

BioGaia's probiotic products with Limosilactobacillus reuteri (formerly known as Lactobacillus reuteri) are among the most scientifically well-documented probiotics in the world. To date the efficacy and safety of BioGaia's different strains of L.

What products contain Lactobacillus reuteri?

Strains are isolated from dairy and meat products and from animal sources. Lactobacillus reuteri is a probiotic culture and a member of the NSLAB population in several cheese varieties (e.g., Cheddar, Grana Padano, Gruyère, Idiazabal, Parmigiano Reggiano, Roncal, and Toma).

What probiotic contains lactobacillus rhamnosus?

Culturelle® isn't just another probiotic. It contains 100% naturally-sourced Lactobacillus rhamnosus GG (LGG®) – the #1 Clinically studied probiotic strain in the world – proven to help support gastrointestinal health, while working around the clock when used as directed.