Can you take excedrin migraine with aleve

We’ve all been there: You have a headache that won’t go away and you have other things to do!

So, what do you reach for first? Coffee? Excedrin? Aleve? Midol?  What’s the best headache medication?

Before you choose what to use for your headache relief, here are some things to consider: Are you taking a blood thinner like warfarin, Eliquis, Xarelto, Pradaxa, or Savaysa? Do you have an upcoming surgery scheduled? Are you already taking a daily aspirin? Do you have a history of peptic ulcers or gastritis? Are you pregnant? How often are you having these headaches?

If you’re taking a blood thinner many of the OTC medications that are sold

Can you take excedrin migraine with aleve

for headache and pain relief can increase your risk of having a serious bleeding problem like bleeding in your stomach, intestines, or brain. Aspirin is particularly risky when taken in larger doses than the 81mg for heart health. When it’s used as a pain reliever the dose is between 200-1000 mg (if you take 2 tablets). These higher doses can result in liver toxicity, and gastrointestinal problems in as many 30-90% of people with pre-existing peptic ulcer or gastritis.

Aspirin is included in many common OTC products such as Goody’s, Midol, Pamprin, Excedrin, Bayer Migraine, BC powder, and Alka-Seltzer to name a few.

Eating along with the medication won’t decrease your risk either. The risk of having a serious bleeding problem increases with age. This risk includes the use of aspirin, ibuprofen, and naproxen and the benefit of using these medications should be carefully weighed against their risks before using them.

If you have any scheduled surgery coming up, the use of aspirin, ibuprofen, naproxen and other blood thinners are generally recommended to be stopped a week beforehand.  You should check with your doctor beforehand.

If you’re pregnant the only safe OTC medication for headache relief is acetaminophen regular strength (Tylenol 325mg). Medications that contain aspirin or NSAIDs like ibuprofen and naproxen can cause serious harm in the third trimester and should be avoided.

If you’re considering using a caffeine-containing medication like Excedrin, here’s some things to know.

  • Caffeine has been shown to cause rebound headaches if over-used, so consider how often you’re using a caffeine-containing medication and how much caffeine you drink.
  • Caffeine can cause an increase in heart rate, and should be avoided in people with cardiac arrhythmias, angina, or a recent history of heart attack.
  • Caffeine can increase anxiety, worsen insomnia, and cause a variety of gastrointestinal effects.

Gosh, maybe I should stop using caffeine!

As always, the best way to use any medication for headache relief is to thoroughly read the labeling and instructions for use before taking it.

If you’d like to talk to a pharmacist now, schedule a time that works for you here:

Can you take excedrin migraine with aleve

Log in and chat with one of our experienced clinical pharmacists to learn more about what medication might be best for you!

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Top answers from doctors based on your search:

A 23-year-old female asked:

Can i take aleve (naproxen) and excedrin migraine at the same time?

Can you take excedrin migraine with aleve

Neurology 20 years experience

NSAID treatments: There is not much use in taking Alleve and Excedrin migraine at the same time. Either one or the other should be used. When people are taking many o... Read More

Created for people with ongoing healthcare needs but benefits everyone.

4k viewsReviewed >2 years ago

A 44-year-old member asked:

What is the difference between aleve, (naproxen) advil and excedrin?

Can you take excedrin migraine with aleve

A Verified Doctoranswered

Rheumatology 53 years experience

See details: Aleve (naproxen) (baproxen) and Advil (ibuprofen) are nonsteroudal antiinflammatory agents that also act as pain relievers. Excedrin has no antiinflam... Read More

Created for people with ongoing healthcare needs but benefits everyone.

3.1k viewsAnswered >2 years ago

A 17-year-old female asked:

Can you take an aleve (naproxen) and an excedrin migraine within the same hour? the aleve (naproxen) isn't helping

Can you take excedrin migraine with aleve

A Verified Doctoranswered

24 years experience

Technically, yes: Aleve (naproxen) contains naprosen, and excedrin contains acetominiphen, two different classes of pain relievers. However, it often takes at least an... Read More

Created for people with ongoing healthcare needs but benefits everyone.

3.8k viewsReviewed >2 years ago

Can you take excedrin migraine with aleve

Pediatrics 32 years experience

Don't do routinely: I wouldn't do it routinely. Hard on the stomach and can cause GI bleeding. Your physician can prescribe better meds for the pain. I'd contact him/her.

Created for people with ongoing healthcare needs but benefits everyone.

3.8k viewsAnswered >2 years ago

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Can I take migraine medicine after taking Aleve?

Interactions between your drugs Using ibuprofen together with naproxen is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

Can you take Excedrin Migraine and naproxen together?

Taking NSAIDs with Excedrin Migraine may increase your risk of side effects. NSAIDs that interact with Excedrin Migraine include: Ibuprofen (Advil or Motrin) Naproxen (Aleve or Naprosyn)

What can you not take with Excedrin Migraine?

Be sure to talk with your doctor before taking Excedrin Migraine if you use any of the following medications: blood thinners such as warfarin, rivaroxaban, and apixaban. nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, 81-mg or 325-mg aspirin, enteric-coated aspirin, and celecoxib.

Can you take Advil and Excedrin Migraine at the same time?

It is not a good idea to take them together because Advil (ibuprofen) is a non-steriodal anti-inflammatory drug pain reliever and Excedrin is also a pain reliever that contains acetaminophen, aspirin and caffeine.