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Sponsor: Information provided by (Responsible Party): Paul Sorum, MD, Albany Medical College Brief Summary: Comparative-effectiveness study of the treatment of acute bacterial sinusitis with amoxicillin/clavulanate 875mg/125mg bid for 7 days with or without the addition of immediate-release amoxicillin 875 mg bid x 7 days. .
Detailed Description: Double-blind comparative-effectiveness study of the treatment of acute bacterial sinusitis with standard dose of amoxicillin/clavulanate 875mg/125mg bid for 7 days, as recommended by the Infectious Disease Society of America, with or without the addition of immediate-release amoxicillin 875 mg bid x 7 days. The study aims are 1) to confirm, or not, our recent findings of more rapid improvement in overall symptoms with the additional amoxicillin, but also of more frequent diarrhea and vaginal yeast infections and 2) to assess, from the participants' point of view, the balance between improvement and adverse effects. Layout table for study information
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Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. Layout table for eligibility information
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Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03431337 Layout table for location information
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Documents provided by Paul Sorum, MD, Albany Medical College: Chow AW, Benninger MS, Brook I, Brozek JL, Goldstein EJ, Hicks LA, Pankey GA, Seleznick M, Volturo G, Wald ER, File TM Jr; Infectious Diseases Society of America. IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Clin Infect Dis. 2012 Apr;54(8):e72-e112. doi: 10.1093/cid/cir1043. Epub 2012 Mar 20. Layout table for additonal information
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How long do you take AMOX CLAV for sinus infection?What are the best antibiotics for a sinus infection? If your symptoms don't get better after about 7 days, your healthcare provider is more likely to prescribe an antibiotic. The recommended choices are amoxicillin or amoxicillin/potassium clavulanate (Augmentin) for 5 to 10 days.
What is the best antibiotic for a sinus infection?What are the most common antibiotics used for sinusitis?. Amoxicillin remains the drug of choice for acute, uncomplicated bacterial sinusitis. ... . Azithromycin is an alternative treatment for patients who are allergic to amoxicillin.. Is 5 days of amoxicillin enough for sinus infection?“But the recommendations have changed on this because subsequent studies have shown the opposite is true, that in fact if the patient is responding to treatment, five to seven days is safe and is usually enough,” Meropol added. “A longer treatment is not usually needed.”
Does AMOX K CLAV 875 125 mg treat sinus infection?Acute sinusitis is a common outpatient diagnosis and is typically treated with antibiotics even though the current recommended regimen (875 mg of amoxicillin with 125 mg of clavulanate by mouth twice a day)1 has been shown in clinical trials to provide only minimal benefit beyond placebo.
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